British Air Force Typhoon FGR4s have conducted a mission with France's air force in a coordinated attack targeting an underground arms cache in Syria used by the IS group, according to the British defence ministry.
The location, identified by surveillance, was believed to be housing weapons and explosive materials, the statement said, and was located in hills just to the north of the historic site of Palmyra in Syria's central region.
"Our aircraft used precision-guided Paveway IV munitions to strike a series of approach shafts down to the site... preliminary assessments suggest the objective was successfully hit," officials stated.
There was no sign of any civilian casualties in the attack late on Saturday and each participating jet returned to base without incident, the MoD added.
The Typhoon fighters were backed up by a Voyager tanker plane.
Daesh - alternatively referred to as Daesh - imposed extremist governance over large swathes of Syria and Iraq until 2019.
"This action underscores our UK leadership, and resolve to stand shoulder to shoulder with our partners, to eradicate any resurgence of IS and their violent and radical beliefs in the area," the British Defence Secretary the minister stated.
British military aircraft have performed surveillance missions over Syria to "deter any attempted resurgence" of IS subsequent to its defeat at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank the personnel of our armed forces involved in this mission for their professionalism and their bravery," the Defence Secretary said. "Including them were thousands of British personnel stationed over the festive period. This operation, to remove dangerous terrorists who endanger our safety, shows how UK forces are ready to step up, all year round, ensuring Britain's security within its borders and influential overseas."
Last December, the American forces conducted what it described as a "large-scale strike" targeting IS targets in the country, after an attack killed two American soldiers and a local interpreter in the Palmyra area.
The U.N. reports Islamic State still maintains between 5,000 and 7,000 combatants in Iraq and Syria.